22-250 Ammo

Especially popular among prairie dog hunters, the .22-250 is known for its ability to remain on course in windy conditions. Some hunters use .22-250 ammo for deer hunting, but it mainly shines in long-range varmint and predator hunting uses. Learn More

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  1. Fiocchi 22-250 Rem Ammo - 20 Rounds of 55 Grain PSP Ammunition

    14 In stock now

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    Image For 20 Rounds Of 55 Grain PSP Boxer Brass 22-250 Rem Fiocchi Ammunition
    $18.00 Price

    Qty:

    • 20 Rounds
    • Made by Fiocchi

    • New Condition
    • 20 Rounds
    • Made by Fiocchi
    • Foreign Discount Range
    • 90¢ Cost Per Round
    • Fiocchi SKU 22250B
    • UPC 762344707433
  2. Federal Fusion 22-250 Rem Ammo - 20 Rounds of 55 Grain SP Ammunition

    39 In stock now

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    Image For 20 Rounds Of 55 Grain SP Boxer Brass 22-250 Rem Federal Ammunition
    $18.50 Price

    Qty:

    • 20 Rounds
    • Made by Federal

    • New Condition
    • 20 Rounds
    • Made by Federal
    • American-made Hunting
    • 92.5¢ Cost Per Round
    • Federal SKU F22250FS1
    • UPC 029465061593
  3. Federal 22-250 Rem Ammo - 20 Rounds of 55 Grain SP Ammunition

    86 In stock now

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    Image For 20 Rounds Of 55 Grain SP Boxer Brass 22-250 Rem Federal Ammunition
    $18.99 Price

    Qty:

    • 20 Rounds
    • Made by Federal

    • New Condition
    • 20 Rounds
    • Made by Federal
    • American-made Discount Hunting
    • 95¢ Cost Per Round
    • Federal SKU 22250A
    • UPC 029465088231
  4. Nosler Varmageddon Ammunition 22-250 Rem Ammo - 20 Rounds of 55 Grain Flat Base Hollow-Point (FBHP) Ammunition

    10 In stock now

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    Image For 20 Rounds Of 55 Grain Flat Base Hollow-Point (FBHP) Boxer Brass 22-250 Rem Nosler Ammunition Ammunition
    $20.00 Price

    Qty:

    • 20 Rounds
    • Made by Nosler Ammunition

    • New Condition
    • 20 Rounds
    • Made by Nosler Ammunition
    • American-made Discount Hunting
    • 55 Grain
    • Flat Base Hollow-Point (FBHP) Bullet
    • Brass Casing
    • Boxer Primer
    • $1.00 Cost Per Round
    • Nosler Ammunition SKU 65150
    • UPC 054041651509
  5. Federal Premium 22-250 Rem Ammo - 20 Rounds of 55 Grain Nosler Ballistic Tip Ammunition

    11 In stock now

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    Image For 20 Rounds Of 55 Grain Nosler Ballistic Tip Boxer Brass 22-250 Rem Federal Ammunition
    $20.50 Price

    Qty:

    • 20 Rounds
    • Made by Federal

    • New Condition
    • 20 Rounds
    • Made by Federal
    • American-made Range
    • $1.03 Cost Per Round
    • Federal SKU P22250F
    • UPC 029465096588
  6. Hornady 22-250 Rem Ammo - 20 Rounds of 40 Grain V-MAX Ammunition

    13 In stock now

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    Image For 20 Rounds Of 40 Grain V-MAX Boxer Brass 22-250 Rem Hornady Ammunition
    $20.75 Price

    Qty:

    • 20 Rounds
    • Made by Hornady

    • New Condition
    • 20 Rounds
    • Made by Hornady
    • American-made Discount Range
    • $1.04 Cost Per Round
    • Hornady SKU 8335
  7. Winchester 22-250 Rem Ammo - 20 Rounds of 64 Grain PSP Ammunition

    18 In stock now

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    Image For 20 Rounds Of 64 Grain PSP Boxer Brass 22-250 Rem Winchester Ammunition
    $25.50 Price

    Qty:

    • 20 Rounds
    • Made by Winchester

    • New Condition
    • 20 Rounds
    • Made by Winchester
    • American-made Hunting
    • $1.28 Cost Per Round
    • Winchester SKU X222502
    • UPC 020892215115
  8. Winchester Ballistic SilverTip 22-250 Rem Ammo - 20 Rounds of 55 Grain Polymer Tipped Ammunition

    11 In stock now

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    Image For 20 Rounds Of 55 Grain Polymer Tipped Boxer Brass 22-250 Rem Winchester Ammunition
    $28.00 Price

    Qty:

    • 20 Rounds
    • Made by Winchester

    • New Condition
    • 20 Rounds
    • Made by Winchester
    • American-made Discount Hunting
    • 55 Grain
    • Polymer Tipped Bullet
    • Brass Casing
    • Boxer Primer
    • $1.40 Cost Per Round
    • Winchester SKU SBST22250B
    • UPC 020892213920
  9. Barnes 22-250 Rem Ammo - 20 Rounds of 50 Grain TSX Ammunition

    4 In stock now

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    Image For 20 Rounds Of 50 Grain TSX Boxer Brass 22-250 Rem Barnes Ammunition
    $29.25 Price

    Qty:

    • 20 Rounds
    • Made by Barnes

    • New Condition
    • 20 Rounds
    • Made by Barnes
    • American-made Hunting
    • $1.46 Cost Per Round
    • Barnes SKU 22008
    • UPC 716876022458
  10. Federal Vital-Shok 22-250 Rem Ammo - 20 Rounds of 60 Grain Nosler Partition Ammunition

    17 In stock now

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    Image For 20 Rounds Of 60 Grain Nosler Partition Boxer Brass 22-250 Rem Federal Ammunition
    $29.99 Price

    Qty:

    • 20 Rounds
    • Made by Federal

    • New Condition
    • 20 Rounds
    • Made by Federal
    • American-made Hunting
    • $1.50 Cost Per Round
    • Federal SKU P22250G
    • UPC 029465096724
  11. Black Hills Gold Ammunition 22-250 Rem Ammo - 20 Rounds of 50 Grain V-MAX Ammunition

    9 In stock now

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    Image For 20 Rounds Of 50 Grain V-MAX Boxer Brass 22-250 Rem Black Hills Ammunition Ammunition
    $30.59 Price

    Qty:

    • 20 Rounds
    • Made by Black Hills Ammunition

    • New Condition
    • 20 Rounds
    • Made by Black Hills Ammunition
    • American-made Hunting
    • $1.53 Cost Per Round
    • Black Hills Ammunition SKU 1C22250BHGN1
    • UPC 612710120987
  12. Black Hills Ammunition 22-250 Rem Ammo - 20 Rounds of 36 Grain Varmint Grenade HP Ammunition

    15 In stock now

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    Image For 20 Rounds Of 36 Grain HP Boxer Brass 22-250 Rem Black Hills Ammunition Ammunition
    $33.15 Price

    Qty:

    • 20 Rounds
    • Made by Black Hills Ammunition

    • New Condition
    • 20 Rounds
    • Made by Black Hills Ammunition
    • American-made Discount Hunting
    • $1.66 Cost Per Round
    • Black Hills Ammunition SKU 1C22250BHGN3
    • UPC 612710123865
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The .22-250 Remington cartridge was developed as a collaboration between Grosvenor Wotkyns, J.E. Gebby and J.E. Smith in 1937, initially designed as a caliber for long-range varmint hunting up to 400 yards. They modified a .250 Savage case (which itself was modified from a .30-06 cartridge) by decreasing the neck size to accept a .224 caliber bullet. An interesting fact about the .22-250 is that it is possible to load the cartridge to achieve muzzle velocities that range from 1,500 to 4,500 feet per second. Performance across this large spectrum of velocity is reportedly consistent, as grouping is good, independent of velocity. Bullets weigh between 35 and 64 grains, and bullet choices range from PSP to V-Max – allowing a single caliber to accomplish a wide range of tasks.

The .22-250 Remington was no stranger to military service in the 1980s. For urban sniping operations, the Australian Special Air Service employed this cartridge to decrease the risk of ricochet as well as over-penetration.

Most major manufacturers have a rifle available for the .22-250 with many different actions, yet one of the most popular is built by the company that developed the cartridge – Remington. Bolt action is the most common type for these rifles as varmint hunters are partial to them.

The .22-250 maintains its popularity due to its excellent accuracy and mild recoil, and the ammunition is widely available at price points similar to other .22 caliber centerfire ammo. It performs well for a variety of applications over wide ranges (it's even a good choice for hunting deer-sized game as far out as 100 yards), and can be depended upon for consistency. A gun writer once wrote that the cartridge was “boringly accurate,” a reference to the round's predictable performance – certainly no insult for this great varmint cartridge.