22-250 Ammo

Especially popular among prairie dog hunters, the .22-250 is liked because of its ability to remain on course in windy conditions. Some hunters even use the .22-250 for deer hunting, but it really shines in long range varmint and predator hunting uses. Learn More

Live Inventory

Set Descending Direction
per page
  1. Sellier and Bellot 22-250 Rem Ammo - 20 Rounds of 55 Grain SP Ammunition

    22 In stock now

    Submit A Review

    Image For 20 Rounds Of 55 Grain SP Boxer Brass 22-250 Rem Sellier and Bellot Ammunition
    $16.29 Price

    Qty:

    • 20 Rounds
    • Made by Sellier and Bellot

  2. Sellier Bellot 22-250 Rem Ammo - 20 Rounds of 55 Grain SBT Ammunition

    52 In stock now

    Submit A Review

    Image For 20 Rounds Of 55 Grain SBT Boxer Brass 22-250 Rem Sellier and Bellot Ammunition
    $17.50 Price

    Qty:

    • 20 Rounds
    • Made by Sellier and Bellot

  3. Fiocchi 22-250 Rem Ammo - 20 Rounds of 55 Grain PSP Ammunition

    86 In stock now

    Submit A Review

    Image For 20 Rounds Of 55 Grain PSP Boxer Brass 22-250 Rem Fiocchi Ammunition
    $18.00 Price

    Qty:

    • 20 Rounds
    • Made by Fiocchi

    • New Condition
    • 20 Rounds
    • Made by Fiocchi
    • Foreign Discount Range
    • 90¢ Cost Per Round
    • Fiocchi SKU 22250B
    • UPC 762344707433
  4. Federal Fusion 22-250 Rem Ammo - 20 Rounds of 55 Grain SP Ammunition

    31 In stock now

    Submit A Review

    Image For 20 Rounds Of 55 Grain SP Boxer Brass 22-250 Rem Federal Ammunition
    $18.25 Price

    Qty:

    • 20 Rounds
    • Made by Federal

    • New Condition
    • 20 Rounds
    • Made by Federal
    • American-made Hunting
    • 91.3¢ Cost Per Round
    • Federal SKU F22250FS1
    • UPC 029465061593
  5. Federal 22-250 Rem Ammo - 20 Rounds of 55 Grain SP Ammunition

    78 In stock now

    Submit A Review

    Image For 20 Rounds Of 55 Grain SP Boxer Brass 22-250 Rem Federal Ammunition
    $18.50 Price

    Qty:

    • 20 Rounds
    • Made by Federal

    • New Condition
    • 20 Rounds
    • Made by Federal
    • American-made Discount Hunting
    • 92.5¢ Cost Per Round
    • Federal SKU 22250A
    • UPC 029465088231
  6. Federal Premium 22-250 Rem Ammo - 20 Rounds of 55 Grain Nosler Ballistic Tip Ammunition

    50 In stock now

    Submit A Review

    Image For 20 Rounds Of 55 Grain Nosler Ballistic Tip Boxer Brass 22-250 Rem Federal Ammunition
    $20.50 Price

    Qty:

    • 20 Rounds
    • Made by Federal

    • New Condition
    • 20 Rounds
    • Made by Federal
    • American-made Range
    • $1.03 Cost Per Round
    • Federal SKU P22250F
    • UPC 029465096588
  7. Hornady 22-250 Rem Ammo - 20 Rounds of 40 Grain V-MAX Ammunition

    22 In stock now

    Submit A Review

    Image For 20 Rounds Of 40 Grain V-MAX Boxer Brass 22-250 Rem Hornady Ammunition
    $20.75 Price

    Qty:

    • 20 Rounds
    • Made by Hornady

    • New Condition
    • 20 Rounds
    • Made by Hornady
    • American-made Discount Range
    • $1.04 Cost Per Round
    • Hornady SKU 8335
  8. Hornady Superformance 22-250 Rem Ammo - 20 Rounds of 50 Grain V-MAX Ammunition

    13 In stock now

    Submit A Review

    Image For 20 Rounds Of 50 Grain V-MAX Boxer Brass 22-250 Rem Hornady Ammunition
    $21.50 Price

    Qty:

    • 20 Rounds
    • Made by Hornady

    • New Condition
    • 20 Rounds
    • Made by Hornady
    • American-made Hunting
    • $1.08 Cost Per Round
    • Hornady SKU 83366
    • UPC 090255833669
  9. Remington 22-250 Rem Ammo - 20 Rounds of 45 Grain JHP Ammunition

    6 In stock now

    Submit A Review

    Image For 20 Rounds Of 45 Grain JHP Boxer Brass 22-250 Rem Remington Ammunition
    $23.75 Price

    Qty:

    • 20 Rounds
    • Made by Remington

    • New Condition
    • 20 Rounds
    • Made by Remington
    • American-made Range
    • $1.19 Cost Per Round
    • Remington SKU L22503
    • UPC 047700354606
  10. Black Hills Gold Ammunition 22-250 Rem Ammo - 20 Rounds of 50 Grain V-MAX Ammunition

    23 In stock now
    Image For 20 Rounds Of 50 Grain V-MAX Boxer Brass 22-250 Rem Black Hills Ammunition Ammunition
    $25.50 Price

    Qty:

    • 20 Rounds
    • Made by Black Hills Ammunition

    • New Condition
    • 20 Rounds
    • Made by Black Hills Ammunition
    • American-made Hunting
    • $1.28 Cost Per Round
    • Black Hills Ammunition SKU 1C22250BHGN1
    • UPC 612710120987
  11. Black Hills Ammunition 22-250 Rem Ammo - 20 Rounds of 36 Grain Varmint Grenade HP Ammunition

    22 In stock now
    Image For 20 Rounds Of 36 Grain HP Boxer Brass 22-250 Rem Black Hills Ammunition Ammunition
    $27.50 Price

    Qty:

    • 20 Rounds
    • Made by Black Hills Ammunition

    • New Condition
    • 20 Rounds
    • Made by Black Hills Ammunition
    • American-made Discount Hunting
    • $1.38 Cost Per Round
    • Black Hills Ammunition SKU 1C22250BHGN3
    • UPC 612710123865
  12. Winchester Ballistic SilverTip 22-250 Rem Ammo - 20 Rounds of 55 Grain Polymer Tipped Ammunition

    31 In stock now
    Image For 20 Rounds Of 55 Grain Polymer Tipped Boxer Brass 22-250 Rem Winchester Ammunition
    $28.00 Price

    Qty:

    • 20 Rounds
    • Made by Winchester

    • New Condition
    • 20 Rounds
    • Made by Winchester
    • American-made Discount Hunting
    • 55 Grain
    • Polymer Tipped Bullet
    • Brass Casing
    • Boxer Primer
    • $1.40 Cost Per Round
    • Winchester SKU SBST22250B
    • UPC 020892213920
  13. Barnes 22-250 Rem Ammo - 20 Rounds of 50 Grain TSX Ammunition

    19 In stock now

    Submit A Review

    Image For 20 Rounds Of 50 Grain TSX Boxer Brass 22-250 Rem Barnes Ammunition
    $29.25 Price

    Qty:

    • 20 Rounds
    • Made by Barnes

    • New Condition
    • 20 Rounds
    • Made by Barnes
    • American-made Hunting
    • $1.46 Cost Per Round
    • Barnes SKU 22008
    • UPC 716876022458
  14. Federal Vital-Shok 22-250 Rem Ammo - 20 Rounds of 60 Grain Nosler Partition Ammunition

    6 In stock now
    Image For 20 Rounds Of 60 Grain Nosler Partition Boxer Brass 22-250 Rem Federal Ammunition
    $29.99 Price

    Qty:

    • 20 Rounds
    • Made by Federal

    • New Condition
    • 20 Rounds
    • Made by Federal
    • American-made Hunting
    • $1.50 Cost Per Round
    • Federal SKU P22250G
    • UPC 029465096724
Set Descending Direction
per page

The .22-250 Remington cartridge was developed in 1937 as a collaboration of Grosvenor Wotkyns, J.E. Gebby and J.E. Smith. They modified a .250 Savage case (which itself was modified from a .30-06 cartridge) by decreasing the neck size to accept a .224 caliber bullet. An interesting fact about the .22-250 is that it is possible to load the cartridge to achieve muzzle velocities that range from 1,500 feet per second to 4,500 feet per second. Performance across this large spectrum of velocity is reportedly consistent, as grouping is good, independent of velocity. Bullets weight between 35 and 64 grains, and bullet choices range from PSP to V-Max, allowing a single caliber to accomplish wide range of tasks.

This cartridge was designed initially as a caliber for long range varmint hunting as far out as 400 yards. The cartridge, with its high velocity and resulting energy, is even a good choice for hunting deer sized game as far out as 100 yards. The .22-250 Remington saw military service in the 1980’s. For urban sniping operations, the Australian Special Air Service employed this cartridge to decrease the risk of ricochet as well as over penetration.

Most major manufacturers have a rifle available for the .22-250 Remington with many different actions, yet one of the most popular rifles is built by the company that developed the cartridge, Remington.  Bolt action is the most common type for these rifles as varmint hunters, the intended audience for this cartridge, are partial to bolt action rifles. 

The .22-250 maintains its popularity due to its excellent accuracy and mild recoil. The ammunition is widely available at price points similar to other .22 caliber center fire ammo. The .22-250 performs well for many applications over wide ranges and can be depended upon for consistency. One gun writer wrote that the cartridge was “boringly accurate,” a reference to the predictable performance of the .22-250, certainly no insult for this great varmint cartridge.