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22-250 Ammo For Sale

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Especially popular among prairie dog hunters, the .22-250 is known for its ability to maintain its course in windy conditions. Some hunters use .22-250 ammo for deer hunting, but it shines for long-range varmint and predator hunting. Learn More
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  1. Fiocchi 22-250 Rem Ammo - 20 Rounds of 55 Grain PSP Ammunition

    Image of Fiocchi 22-250 Rem Ammo - 20 Rounds of 55 Grain PSP Ammunition
    $24.99
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    50 In stock now

    1 2 3 4 5 6 7 8 9 +10
    Bullet type PSP
    Primer Type Boxer
    Casing Type Brass
    Condition New
    Muzzle Velocity 3650 FPS
    Muzzle Energy 1627 ft lbs
    • 20 Rounds
    • $1.25 per round
    • Made by Fiocchi

  2. Remington 22-250 Rem Ammo - 20 Rounds of 50 Grain JHP Ammunition

    Image of Remington 22-250 Rem Ammo - 20 Rounds of 50 Grain JHP Ammunition
    $27.99
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    86 In stock now

    1 2 3 4 5 6 7 8 9 +10
    Bullet type JHP
    Primer Type Boxer
    Casing Type Brass
    Condition New
    Muzzle Velocity 3820 FPS
    Muzzle Energy 1620 ft lbs

  3. Federal 22-250 Rem Ammo - 20 Rounds of 55 Grain SP Ammunition

    Image of Federal 22-250 Rem Ammo - 20 Rounds of 55 Grain SP Ammunition
    $29.99
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    2 In stock now

    1 2 3 4 5 6 7 8 9 +10
    Bullet type SP
    Primer Type Boxer
    Casing Type Brass
    Condition New
    Muzzle Velocity 3650 FPS
    Muzzle Energy 1627 ft lbs
    • 20 Rounds
    • $1.5 per round
    • Made by Federal

  4. Hornady Superformance 22-250 Rem Ammo - 20 Rounds of 50 Grain V-MAX Ammunition

    Image of Hornady Superformance 22-250 Rem Ammo - 20 Rounds of 50 Grain V-MAX Ammunition
    $29.99
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    1 In stock now

    1 2 3 4 5 6 7 8 9 +10
    Bullet type V-MAX
    Primer Type Boxer
    Casing Type Brass
    Condition New
    Muzzle Velocity 4000 FPS
    Muzzle Energy 1776 ft lbs
    • 20 Rounds
    • $1.4 to $1.5 per round
    • Made by Hornady

  5. Winchester 22-250 Rem Ammo - 20 Rounds of 64 Grain PSP Ammunition

    Image of Winchester 22-250 Rem Ammo - 20 Rounds of 64 Grain PSP Ammunition
    $34.99
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    69 In stock now

    1 2 3 4 5 6 7 8 9 +10
    Bullet type PP
    Primer Type Boxer
    Casing Type Brass
    Condition New
    Muzzle Velocity 3500 FPS
    Muzzle Energy 1741 ft lbs

  6. Barnes 22-250 Rem Ammo - 20 Rounds of 50 Grain TSX Ammunition

    Image of Barnes 22-250 Rem Ammo - 20 Rounds of 50 Grain TSX Ammunition
    $39.99
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    48 In stock now

    1 2 3 4 5 6 7 8 9 +10
    Bullet type TSX
    Primer Type Boxer
    Casing Type Brass
    Condition New
    Muzzle Velocity 3830 FPS
    Muzzle Energy 1629 ft lbs
    • 20 Rounds
    • $2 per round
    • Made by Barnes

  7. Black Hills Ammunition 22-250 Rem Ammo - 20 Rounds of 36 Grain Varmint Grenade HP Ammunition

    Image of Black Hills Ammunition 22-250 Rem Ammo - 20 Rounds of 36 Grain Varmint Grenade HP Ammunition
    $49.99
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    12 In stock now

    1 2 3 4 5 6 7 8 9 +10
    Bullet type HP
    Primer Type Boxer
    Casing Type Brass
    Condition New
    Muzzle Velocity 4250 FPS
    Muzzle Energy 1444 ft lbs
    • 20 Rounds
    • $2.5 per round
    • Made by Black Hills Ammunition

History of 22-250 Ammo

The .22-250 Remington cartridge was developed in 1937 as a collaboration between Grosvenor Wotkyns, J.E. Gebby, and J.E. Smith as a long-range (400 yards) varmint hunting cartridge. he .22-250 Remington was no stranger to military service in the 1980s. The Australian Special Air Service employed this cartridge for urban sniping operations to decrease the risk of ricochet and over-penetration.

The .22-250 maintains its popularity due to its excellent accuracy and mild recoil. It is widely available at price points similar to those of other .22 caliber centerfire ammo. It performs well for various applications over wide ranges and is ridiculously consistent. A gun writer once wrote that the cartridge was “boringly accurate,” referencing the round's predictable performance—indeed, no insult for this excellent varmint cartridge.

How Does The 22-250 Rem Compare To Other Calibers?

Caliber Recoil Pros Cons
204 Ruger 22-250 Rem has more 22-250 Rem has more stopping power and more abundant ammo selection 22-250 Rem has slightly heavier recoil and worse trajectory
223 Remington 22-250 Rem has more 22-250 Rem has more stopping power and flatter trajectory 22-250 Rem has slightly heavier recoil and more expensive ammo
22 Nosler 22-250 Rem has slightly more 22-250 Rem has flatter trajectory and more ammo options 22-250 Rem has slightly heavier recoil and less than ideal for deer hunting
224 Valkyrie Nearly identical 22-250 Rem has better short-range trajectory and better for hunting 22-250 Rem has worse long-range trajectory and slightly more expensive ammo

You can also check out our in-depth look at 22-250 ballistics from all of the popular ammo manufacturers if you're searching for ballistics data for your favorite factory 22-250 load.

Molly Carter
Written by
Molly Carter