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22-250 Ammo For Sale

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Especially popular among prairie dog hunters, the .22-250 is known for its ability to remain on course in windy conditions. Some hunters use .22-250 ammo for deer hunting, but it mainly shines in long-range varmint and predator hunting uses. Learn More
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  1. Remington 22-250 Rem Ammo - 40 Rounds of 50 Grain JHP Ammunition

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    $49.99
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    8 In stock now

    1 2 3 4 5 6 7 8 9 +10
    Bullet type Jacketed Hollow-Point (JHP)
    Primer Type Boxer
    Casing Type Brass
    Condition New
    Muzzle Velocity 3820 FPS
    Muzzle Energy 1620 ft lbs
    • 40 Rounds
    • $1.25 per round
    • Made by Remington

  2. Remington 22-250 Rem Ammo - 20 Rounds of 50 Grain JHP Ammunition

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    $27.99
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    104 In stock now

    1 2 3 4 5 6 7 8 9 +10
    Bullet type Jacketed Hollow-Point (JHP)
    Primer Type Boxer
    Casing Type Brass
    Condition New
    Muzzle Velocity 3820 FPS
    Muzzle Energy 1620 ft lbs

  3. Remington 22-250 Rem Ammo - 20 Rounds of 45 Grain JHP Ammunition

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    $27.99
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    7 In stock now

    1 2 3 4 5 6 7 8 9 +10
    Bullet type Jacketed Hollow-Point (JHP)
    Primer Type Boxer
    Casing Type Brass
    Condition New
    Muzzle Velocity 4000 FPS
    Muzzle Energy 1598 ft lbs

  4. Hornady Superformance 22-250 Rem Ammo - 20 Rounds of 50 Grain V-MAX Ammunition

    Image of Hornady Superformance 22-250 Rem Ammo - 20 Rounds of 50 Grain V-MAX Ammunition
    $29.99
    As low as $28.00 in bulk
    • $28.00 each if you buy 5 - save 7%
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    119 In stock now

    1 2 3 4 5 6 7 8 9 +10
    Bullet type V-MAX
    Primer Type Boxer
    Casing Type Brass
    Condition New
    Muzzle Velocity 4000 FPS
    Muzzle Energy 1776 ft lbs
    • 20 Rounds
    • $1.4 to $1.5 per round
    • Made by Hornady

  5. Winchester 22-250 Rem Ammo - 20 Rounds of 64 Grain PSP Ammunition

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    $34.99
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    89 In stock now

    1 2 3 4 5 6 7 8 9 +10
    Bullet type Power-Point (PP)
    Primer Type Boxer
    Casing Type Brass
    Condition New
    Muzzle Velocity 3500 FPS
    Muzzle Energy 1741 ft lbs

  6. Barnes 22-250 Rem Ammo - 20 Rounds of 50 Grain TSX Ammunition

    Image of Barnes 22-250 Rem Ammo - 20 Rounds of 50 Grain TSX Ammunition
    $39.99
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    61 In stock now

    1 2 3 4 5 6 7 8 9 +10
    Bullet type TSX
    Primer Type Boxer
    Casing Type Brass
    Condition New
    Muzzle Velocity 3830 FPS
    Muzzle Energy 1629 ft lbs
    • 20 Rounds
    • $2 per round
    • Made by Barnes

  7. Black Hills Ammunition 22-250 Rem Ammo - 20 Rounds of 36 Grain Varmint Grenade HP Ammunition

    Image of Black Hills Ammunition 22-250 Rem Ammo - 20 Rounds of 36 Grain Varmint Grenade HP Ammunition
    $49.99
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    20 In stock now

    1 2 3 4 5 6 7 8 9 +10
    Bullet type Hollow-Point (HP)
    Primer Type Boxer
    Casing Type Brass
    Condition New
    Muzzle Velocity 4250 FPS
    Muzzle Energy 1444 ft lbs
    • 20 Rounds
    • $2.5 per round
    • Made by Black Hills Ammunition

History of 22-250 Ammo

The .22-250 Remington cartridge was developed as a collaboration between Grosvenor Wotkyns, J.E. Gebby and J.E. Smith in 1937, initially designed as a caliber for long-range varmint hunting up to 400 yards. They modified a .250 Savage case (which itself was modified from a .30-06 cartridge) by decreasing the neck size to accept a .224 caliber bullet. An interesting fact about the .22-250 is that it is possible to load the cartridge to achieve muzzle velocities that range from 1,500 to 4,500 feet per second. Performance across this large spectrum of velocity is reportedly consistent, as grouping is good, independent of velocity. Bullets weigh between 35 and 64 grains, and bullet choices range from PSP to V-Max – allowing a single caliber to accomplish a wide range of tasks.

The .22-250 Remington was no stranger to military service in the 1980s. For urban sniping operations, the Australian Special Air Service employed this cartridge to decrease the risk of ricochet as well as over-penetration.

Most major manufacturers have a rifle available for the .22-250 with many different actions, yet one of the most popular is built by the company that developed the cartridge – Remington. Bolt action is the most common type for these rifles as varmint hunters are partial to them.

The .22-250 maintains its popularity due to its excellent accuracy and mild recoil, and the ammunition is widely available at price points similar to other .22 caliber centerfire ammo. It performs well for a variety of applications over wide ranges (it's even a good choice for hunting deer-sized game as far out as 100 yards), and can be depended upon for consistency. A gun writer once wrote that the cartridge was “boringly accurate,” a reference to the round's predictable performance – certainly no insult for this great varmint cartridge.

22-250 Ballistics: Chart of Average 22-250 Ballistics

Note: This information comes from the manufacturer and is for informational purposes only. The actual ballistics obtained with your firearm can vary considerably from the advertised ballistics. Also, ballistics can vary from lot to lot with the same brand and type load.

22-250 Bullet WEIGHT Muzzle VELOCITY (fps) Muzzle ENERGY (ft. lbs.) TRAJECTORY (in.)
  Muzzle 100 yds. 200 yds. 300 yds. 400 yds. Muzzle 100 yds. 200 yds. 300 yds. 400 yds. 100 yds. 200 yds. 300 yds. 400 yds.
35 Grain 4450 3736 3128 2598 2125 1539 1085 761 524 351 6.5 0 -4.1 -13.4
40 Grain 4000 3320 2720 2200 1740 1420 980 660 430 265 2 1.8 -3 -16
40 Grain 4150 3553 3033 2570 2151 1530 1121 817 587 411 0.6 0 -4.4 -14.2
45 Grain Green 4000 3293 2690 2159 1696 1598 1084 723 466 287 1.7 1.7 -3.2 -15.7
50 Grain 3725 3264 2641 2455 2103 1540 1183 896 669 491 0.89 0 -5.23 -16.3
52 Grain 3680 3137 2656 2222 1832 1654 1201 861 603 410 2 1.3 -4 -17
55 Grain 3680 3137 2656 2222 1832 1654 1201 861 603 410 2 1.3 -4 -17
60 Grain 3600 3195 2826 2485 2169 1727 1360 1064 823 627 2 2 -2.4 -12.3
64 Grain 3425 2988 2591 2228 1897 1667 1269 954 705 511 1.2 0 -6.4 -20
Molly Carter
Written by
Molly Carter